ops...another site hacked :-)

today the victim is:

www.isbr.lanl.gov

 

Hi-Tech Hate Crew

was here :-)

 

B4dBoy dedicates this one to Simona: please remember I WILL LOVE YOU FOREVER

naDrol Rah'S dedicates this one to his love Linda

E-@ack dedicates this to Laura

DauthiJackal dedicates this one to his love Giorgia



note to sysadmin: no file has been deleted (?) or looked at , original index page is here

mail us at hitech_hate@email.com fan mails only are welcome don't expect any response, we won't reply anyone and above all: don't ask us how to hack, learn by yourselves instead

r system funded by the U.S. Department of Energy.  Anyone using this system consents to monitoring of this use by system or security personnel.

Group leader: Chris Wood

 The Biophysics Group (P-21) was founded in 1988 with the goal of applying the scientific and technical resources of Physics Division to the biosciences. The mission of P-21 is to apply physics knowledge and techniques to increase our understanding of important biological phenomena and to use biological systems to elucidate physical principles of complex phenomena. The group has strengthened existing biological projects within the Division and has initiated new bioscience efforts in a number of directions. Group members are engaged in biophysical research over a wide range of physical scales, including characterization of the structure and dynamics of protein molecules and the implications of those qualities for protein function; ultrasensitive detection and characterization of individual molecules using laser fluorescence; design and implementation of biologically inspired robots and adaptive digital hardware; development, validation, and application of noninvasive techniques for the measurement of human brain function; development of nonbiological applications of low-field magnetic sensors; and development of three-dimensional computational models of the human brain.


People:

P-21 roster
P-21 homepages

Projects:

Low-Field Magnetic Sensors
R. Kraus

The Los Alamos Biophysics group is developing several sensors for weak magnetic fields. These include: 1) a 120 sensor system for the human brain; 2) a 12 sensor system for the human heart and other organs; 3) a sensor system for Non-Destructive Evaluation and Corrosion studies; 4) a small system for microstructure examination; 5) a HiTc SQUID system for use with HiTc SQUIDs; and 6) a gravity gradiometer scheme. The use of DSP chips in the SQUID circuits is also being implemented.
Single-Molecule Detection
A. Castro

This project focuses on the development of laser-based techniques for the detection and analysis of biological molecules. Applications to molecular biology and medical diagnosis are being explored.
Protein dynamics and kinetic crystallography

J. Berendzen
Protein dynamics is the study of the conformational motions responsible for biological function and the underlying physics. We use UV/Vis/IR spectroscopy in concert with cryogenic techniques and X-ray crystallography to study the structural foundations of protein reactions. Knowledge of the three-dimensional structures of intermediates in protein-ligand reactions helps us understand the way proteins work and provides the groundwork for manipulating and controlling biomolecules. This can potentially impact many fields, including mechanism-based drug design and bioremediation. 
Brain Imaging and Modeling
J. George
Work is focused in two major areas.
We are involved in the development and application of technologies for functional mapping of the human brain.  The present focus is on the development of experimental and computational methodologies for integrated neuroimaging combining multiple complementary methods: Neural Electromagnetic Methods, MEG and EEG; Anatomical MRI (to define computational geometries), and functional MRI.  This effort is supported by the NIH-lead Human Brain Project.
The second area of research and development is in the area of Advanced Optical Imaging.  The primary target application  is imaging of brain physiology and function, although the technologies are useful in other contexts.  Projects include:  "Virtual Pinhole" Confocal Microscopy;  Confocal and Spectral Endoscopy;  and Photon Migration Tomography.
Robotics and adaptive systems

J. Moses
P-21 has begun investigations into the design, implementation, and application of a variety of adaptive control systems. These include development of biologically inspired, legged robotics with simple, highly robust control circuits; applications of wavelets for feature recognition and data compression; and support for advanced multi-channel data-acquisition systems. This work promises to contribute both to an improved understanding of robotic control and to a variety of applications in which robust, inexpensive adaptive capabilities are required.

Events:

Biomag '96

Related Links:

LANL pages:
Los Alamos National Laboratory
P-Division
Theoretical Biology and Biophysics (T-10)
Bioscience and Biotechnology (CST-4)
Structural Biology (LS-8)
Center for Non-Linear Studies (CNLS)
Human Genome Project
Medical Data Analysis Projects
Integrated Structural Biology Resource
Beamline X8C at the National Synchrotron Light Source
Medical Physics and Imaging Resources

MST
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Comments to www@biophysics.lanl.gov